Terminology Service for NFDI4Health
CD8_alpha-positive CD11b-negative dendritic cell
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http://purl.obolibrary.org/obo/CL_0001000
CD8_alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8_alpha-positive. [ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346585 http://purl.obolibrary.org/obo/go/references/0000031 ]
Term info
Label
CD8_alpha-positive CD11b-negative dendritic cell
Synonyms
- DC.8+
comment
Cells are defined as having a disposition to secreting inflammatory cytokines. Originally described in the dendritic cell ontology (DC_CL:0000013)(PMID:19243617).
has obo namespace
cell
Term relations
Equivalent to:
- conventional dendritic cell and has plasma membrane part some lymphocyte antigen 75 and has plasma membrane part some T-cell surface glycoprotein CD8 alpha chain and capable of some cytokine production and capable of some antigen processing and presentation of exogenous peptide antigen via MHC class I and capable of some positive regulation of inflammatory response and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M
Subclass of:
- myeloid leukocyte
- conventional dendritic cell
- has plasma membrane part some T-cell surface glycoprotein CD8 alpha chain
- capable of some positive regulation of inflammatory response
- lacks_plasma_membrane_part some CD4 molecule
- has plasma membrane part some lymphocyte antigen 75
- capable of some antigen processing and presentation of exogenous peptide antigen via MHC class I
- lacks_plasma_membrane_part some integrin alpha-M
- develops from some pre-conventional dendritic cell