Terminology Service < Semantic Lookup Platform

CD8_alpha-low Langerhans cell

http://purl.obolibrary.org/obo/CL_0001015

CD8_alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8_alpha-low. [ http://purl.obolibrary.org/obo/go/references/0000031 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346585 ]

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Term info

Label

CD8_alpha-low Langerhans cell

comment

These markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000027)(PMID:19243617). They are also CD205-high, CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD285-positive (TLR5), CD286-positive (TLR6), and CD289-positive (TLR9).

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cell

Term relations

Equivalent to:

Langerhans cell and has_high_plasma_membrane_amount some lymphocyte antigen 75 and has_low_plasma_membrane_amount some T-cell surface glycoprotein CD8 alpha chain

Subclass of:

Langerhans cell
has_low_plasma_membrane_amount some T-cell surface glycoprotein CD8 alpha chain
has_high_plasma_membrane_amount some lymphocyte antigen 75