Terminology Service for NFDI4Health
common dendritic progenitor
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http://purl.obolibrary.org/obo/CL_0001029
Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. [ http://www.ncbi.nlm.nih.gov/pubmed/19286519 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/17922016 http://www.ncbi.nlm.nih.gov/pubmed/16551251 ]
Term info
Label
common dendritic progenitor
Synonyms
- CDP
- common dendritic precursor
- pro-DCs
comment
Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617).
has obo namespace
cell
Term relations
Equivalent to:
- hematopoietic lineage restricted progenitor cell and has plasma membrane part some receptor-type tyrosine-protein kinase FLT3 and has plasma membrane part some macrophage colony-stimulating factor 1 receptor and has_low_plasma_membrane_amount some mast/stem cell growth factor receptor and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
Subclass of:
- CD115-positive monocyte OR common dendritic progenitor
- material anatomical entity
- myeloid cell
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain
- lacks_plasma_membrane_part some CD4 molecule
- lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- has_low_plasma_membrane_amount some mast/stem cell growth factor receptor
- lacks_plasma_membrane_part some CD3 epsilon
- has plasma membrane part some receptor-type tyrosine-protein kinase FLT3
- lacks_plasma_membrane_part some CD2 molecule
- lacks_plasma_membrane_part some integrin alpha-M
- has plasma membrane part some macrophage colony-stimulating factor 1 receptor
- lacks_plasma_membrane_part some CD14 molecule
- lacks_plasma_membrane_part some neural cell adhesion molecule 1
- lacks_plasma_membrane_part some CD19 molecule
- develops from some macrophage dendritic cell progenitor
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD5
- lacks_plasma_membrane_part some lymphocyte antigen 6G