Terminology Service for NFDI4Health
common myeloid progenitor, CD34-positive
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http://purl.obolibrary.org/obo/CL_0001059
A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. [ http://www.ncbi.nlm.nih.gov/pubmed/16551251 http://www.ncbi.nlm.nih.gov/pubmed/10724173 https://www.worldcat.org/search?q=bn%3A0878932437 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212039 http://www.ncbi.nlm.nih.gov/pubmed/16647566 ]
Term info
Label
common myeloid progenitor, CD34-positive
Synonyms
- common myeloid precursor, CD34-positive
comment
CMP are reportedly CD16-positive, CD32-positive, CD38-positive, CD45RA-negative, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.
has obo namespace
cell
has related synonym
colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte, CFU-GEMM, myeloid stem cell, multipotential myeloid stem cell, CFU-S, pluripotent stem cell (bone marrow)
Term relations
Equivalent to:
- common myeloid progenitor and has_part some transcription factor PU.1 and has_part some CCAAT/enhancer-binding protein alpha and has_part some erythroid transcription factor and has_part some endothelial transcription factor GATA-2 and has plasma membrane part some CD34 molecule and capable of some myeloid leukocyte differentiation and capable of some myeloid dendritic cell differentiation
Subclass of:
- material anatomical entity
- precursor cell
- common myeloid progenitor
- has_part some CCAAT/enhancer-binding protein alpha
- capable of some myeloid dendritic cell differentiation
- has_part some endothelial transcription factor GATA-2
- has_part some erythroid transcription factor
- has plasma membrane part some CD34 molecule
- has_part some transcription factor PU.1