basophil mast progenitor cell
A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa [ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312421 ]
Term info
basophil mast progenitor cell
- BMCP
There may be an intermediate cell type. These cells also CD13-positive, CD16-positive, CD32-positive, and integrin beta 7-positive. Transcription factors: GATA1-positive, MCP-1-positive, mitf-positive, PU.1-positive, and CEBP/a-low.
tmeehan
2010-04-27T12:46:33Z
cell
Term relations
- myeloid lineage restricted progenitor cell and has_part some CCAAT/enhancer-binding protein alpha and has_part some erythroid transcription factor and has_part some endothelial transcription factor GATA-2 and has plasma membrane part some interleukin-5 receptor subunit alpha and has plasma membrane part some mast/stem cell growth factor receptor and capable of some basophil differentiation and capable of some mast cell differentiation and lacks_plasma_membrane_part some high affinity immunoglobulin epsilon receptor subunit alpha and lacks_plasma_membrane_part some transmembrane emp24 domain-containing protein 1
- granulocytopoietic cell
- material anatomical entity
- myeloid cell
- capable of some basophil differentiation
- has_part some CCAAT/enhancer-binding protein alpha
- capable of some mast cell differentiation
- lacks_plasma_membrane_part some transmembrane emp24 domain-containing protein 1
- lacks_plasma_membrane_part some high affinity immunoglobulin epsilon receptor subunit alpha
- has plasma membrane part some mast/stem cell growth factor receptor
- has_part some endothelial transcription factor GATA-2
- has plasma membrane part some interleukin-5 receptor subunit alpha
- develops from some granulocyte monocyte progenitor cell
- has_part some erythroid transcription factor