Fraction D precursor B cell
A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/17582343 http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://www.immgen.org/index_content.html ]
Term info
Fraction D precursor B cell
- Fr. D
- Fraction D pre-B cell
Fraction D precursor B cells are also reportedly CD24-positive and sIgD-negative.
tmeehan
2010-04-28T02:55:16Z
cell
Term relations
- precursor B cell and has plasma membrane part some CD19 molecule and has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45R and has plasma membrane part some interleukin-2 receptor subunit alpha and has plasma membrane part some signal transducer CD24 and has plasma membrane part some complement component C1q receptor and has plasma membrane part some glutamyl aminopeptidase and has_low_plasma_membrane_amount some leukosialin and has_not_completed some immunoglobulin light chain V-J recombination and lacks_plasma_membrane_part some pre-B cell receptor complex
- Fraction B/C precursor B cell
- lacks_plasma_membrane_part some pre-B cell receptor complex
- has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45R
- has_not_completed some immunoglobulin light chain V-J recombination
- has_low_plasma_membrane_amount some leukosialin
- has plasma membrane part some glutamyl aminopeptidase
- has plasma membrane part some interleukin-2 receptor subunit alpha
- develops from some Fraction C' precursor B cell