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CD16-positive myeloid dendritic cell

http://purl.obolibrary.org/obo/CL_0002532

A myeloid dendritic cell found in the blood that is CD16-positive. [ http://www.ncbi.nlm.nih.gov/pubmed/17332250 ]

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Term info

Label

CD16-positive myeloid dendritic cell

Synonyms

CD16+ mDC
CD16-mDC

comment

Normally represent 65-75% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), CD289-positive (TLR9), and CD290-positive (TLR10) by RT-PCR [PMID:17332250]. Upon TLR stimulation, these cells are potent producers of TNF-alpha, while producing little CXCL8 (IL8).

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cell

Term relations

Equivalent to:

myeloid dendritic cell and has plasma membrane part some low affinity immunoglobulin gamma Fc region receptor III and capable of some tumor necrosis factor production

Subclass of:

myeloid dendritic cell
capable of some tumor necrosis factor production
has plasma membrane part some low affinity immunoglobulin gamma Fc region receptor III