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cargo receptor activity

Go to external page http://purl.obolibrary.org/obo/GO_0038024

Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. [ http://www.ncbi.nlm.nih.gov/pubmed/15239958 http://www.ncbi.nlm.nih.gov/pubmed/27903609 ]

Term info

Label

cargo receptor activity

comment

Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport. For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857.

created by

rfoulger

creation date

2011-08-01T02:50:45Z

has broad synonym

transport receptor activity, receptor activity

has narrow synonym

endocytic receptor activity, receptor activity involved in receptor-mediated endocytosis

has obo namespace

molecular_function

id

GO:0038024