Terminology Service for NFDI4Health
integrin alpha-M
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http://purl.obolibrary.org/obo/PR_000001012
An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. [ https://www.uniprot.org/uniprot/P11215 ]
Term info
Label
integrin alpha-M
Synonyms
- CD11 antigen-like family member B
- CD11b
- CR-3 alpha chain
- ITGAM
- cell surface glycoprotein MAC-1 subunit alpha
- leukocyte adhesion receptor MO1
- neutrophil adherence receptor
comment
Category=gene. Requested by=CL.
has obo namespace
protein
has related synonym
CR3A
id
PR:000001012
Term relations
Related from:
has_low_plasma_membrane_amount
- alveolar macrophage
- lymph node macrophage
- splenic red pulp macrophage
- CD27-low, CD11b-low immature natural killer cell
- CD27-high, CD11b-low natural killer cell
- CD103-positive, langerin-positive lymph node dendritic cell
- liver CD103-positive dendritic cell
- CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell
- Kupffer cell
has_high_plasma_membrane_amount
- peritoneal macrophage
- CD27-high, CD11b-high natural killer cell
- CD27-low, CD11b-high natural killer cell
- lymphoid MHC-II-negative classical monocyte
- lymphoid MHC-II-negative non-classical monocyte
- liver CD103-negative dendritic cell
- CD103-negative, langerin-positive lymph node dendritic cell
- CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell
lacks_plasma_membrane_part
- group 2 innate lymphoid cell, mouse
- pre-conventional dendritic cell
- proerythroblast
- megakaryocyte progenitor cell
- reticulocyte
- basophil progenitor cell
- eosinophil progenitor cell
- erythroblast
- mast cell progenitor
- hematopoietic multipotent progenitor cell
- promyelocyte
- splenic marginal zone macrophage
- CD8_alpha-positive CD11b-negative dendritic cell
- common dendritic progenitor
- erythroid progenitor cell, mammalian
- hematopoietic oligopotent progenitor cell, lineage-negative
- langerin-positive dermal dendritic cell
- natural helper lymphocyte
- hematopoietic stem cell
- thymic plasmacytoid dendritic cell
- thymic conventional dendritic cell
- CD11c-low plasmacytoid dendritic cell
- CD8_alpha-negative CD11b-negative dendritic cell