Terminology Service for NFDI4Health
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integrin alpha-X

Go to external page http://purl.obolibrary.org/obo/PR_000001013

An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. [ https://www.uniprot.org/uniprot/P20702 ]

Term info

Label

integrin alpha-X

Synonyms
  • CD11 antigen-like family member C
  • CD11c
  • ITGAX
  • Leu M5
  • leukocyte adhesion glycoprotein p150,95 alpha chain
  • leukocyte adhesion receptor p150,95
database cross reference
comment

Category=gene. Requested by=CL.

id

PR:000001013