Terminology Service for NFDI4Health
islet of Langerhans
Go to external page
http://purl.obolibrary.org/obo/UBERON_0000006
the clusters of hormone-producing cells that are scattered throughout the pancreas [ http://www.informatics.jax.org/searches/AMA.cgi?id=MA:0000127 ]
Term info
Label
islet of Langerhans
Synonyms
- pancreatic insula
- pancreatic islet
Subsets
uberon_slim, efo_slim, pheno_slim
depicted by
http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png
external definition
Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]
fma set term
http://purl.obolibrary.org/obo/FMA_76489
has obo namespace
uberon
has related synonym
island of pancreas, island of Langerhans, islets of Langerhans
homology notes
Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]
id
UBERON:0000006
taxon notes
A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)