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central nervous system

Go to external page http://purl.obolibrary.org/obo/UBERON_0001017

The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. [ https://sourceforge.net/p/geneontology/ontology-requests/11422/ http://www.frontiersinzoology.com/content/7/1/29 http://amigo.geneontology.org/amigo/term/GO:0021551 ]

Term info

Label

central nervous system

Synonyms
  • CNS
  • systema nervosum centrale
database cross reference
Subsets

uberon_slim, cumbo, efo_slim, pheno_slim, vertebrate_core

latin term
systema nervosum centrale [ FMA : 55675 FMA : TA ]

external definition

The brain and spinal cord. Kimmel et al, 1995.[TAO], The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)., Part of the nervous system which includes the brain and spinal cord.[AAO]

has narrow synonym

cerebrospinal axis

homology notes

(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]

id

UBERON:0001017