relationship loss: develops_from forebrain neural tube (TAO:0007041)[TAO]

http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg

The most anterior region the brain including both the telencephalon and diencephalon. Kimmel et al, 1995.[TAO], Most anterior of the three regions of the brain consisting of the telencephalon and diencephalon.[AAO]

FB

uberon

prosencephalon

prosencephalic

In craniate embryos, neural expression of Distal-less-related genes is exclusively in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll is in the anterior three-fourths of the cerebral vesicle, we suggest that this region of the neural tube is homologous to parts of the craniate forebrain. This conclusion is strongly supported by three-dimensional, computer-assisted reconstruction of the neural tube of amphioxus based on serial transmission electron microscopy. At the neuroanatomical level, a number of detailed homologies are indicated between the anterior three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the craniate forebrain. If one assumes that the amphioxus condition fairly represents the nervous system of the proximate ancestor of the craniates, one can suggest that they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG]

UBERON:0001890

• diencephalon

• future forebrain

• forebrain-midbrain boundary

• forebrain neuroblast
• gray matter of forebrain
• white matter of forebrain
• astrocyte of the forebrain
• neuron of the forebrain
• forebrain radial glial cell
• forebrain meninges
• telencephalon
• diencephalon
• basal forebrain
• limbic system