undifferentiated genital tubercle
the embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin [ http://www.informatics.jax.org/accession/anna https://github.com/obophenotype/uberon/issues/1230 ]
Term info
undifferentiated genital tubercle
- undifferentiated genital tubercle
pheno_slim
http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png
The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG], embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]
we assume the EMAPA class is the undifferentiated form based on TS timings
uberon
phallic tubercle, genital tubercle, tuberculum genitale, tuberculum phallicum
In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]
UBERON:0005876
GT development is indistinguishable in male and female mouse embryos until approximately E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP:0011771], All amniotes studied to date initiate external genital development with the formation of paired genital swellings. In mammals, archosaurs, and turtles, these swellings merge to form a single genital tubercle, the precursor of the penis and clitoris[PMID:24960313], todo - add taxon constraints