germinal center
A collection of activated B cells at the center of a secondary follicle, formed after B cells become activated and migrate to the center. [ http://purl.obolibrary.org/obo/CL_tm http://en.wikipedia.org/wiki/Germinal_center https://orcid.org/0000-0002-6601-2165 ]
Term info
germinal center
- central zone of follice
- light zone of follicle
- reaction center of follicle
A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.[GO]
http://purl.obolibrary.org/obo/Germinal_center.svg
uberon
lymhpoid nodule, nodule
UBERON:0010754