Terminology Service for NFDI4Health
JSON

fibroblast

Go to external page http://purl.obolibrary.org/obo/CL_0000057

A connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms.

A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.

A large, flat, oval cell found in connective tissue and responsible for the formation of fibers.

These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative.

Term info

Label

fibroblast

Synonyms
  • mouse embryonic fibroblast
  • primary dermal fibroblast
database cross reference
definition

A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.

definition source

BTO:0000452, NIFSTD:nlx_cell_20090201, CL:0000057

imported from

http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl

see also

URI: http://www.ebi.ac.uk/cellline#fibroblast, EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000496

term editor

Tomasz Adamusiak, James Malone