Terminology Service for NFDI4Health
endothelial cell
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http://purl.obolibrary.org/obo/CL_0000115
From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].
The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart.
Term info
Label
endothelial cell
definition
An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.
definition source
BTO:0001176, CL:0000115
has exact synonym
endotheliocyte
has obo namespace
cell
imported from
http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl
see also
URI: http://www.ebi.ac.uk/cellline#endothelial_cell, EFO_URI: http://www.ebi.ac.uk/efo/EFO_0000467
term editor
James Malone