Terminology Service for NFDI4Health
microglial cell
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http://purl.obolibrary.org/obo/CL_0000129
Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive.
Term info
Label
microglial cell
definition
A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.
has exact synonym
hortega cells, microgliocyte, microglia, brain-resident macrophage
has broad synonym
brain macrophage
has obo namespace
cell
has related synonym
MF.microglia.CNS
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- glial cell and part of some central nervous system and has plasma membrane part some integrin alpha-M and has plasma membrane part some adhesion G protein-coupled receptor E1 and has plasma membrane part some macrosialin and capable of some innate immune response
Subclass of:
- central nervous system macrophage
- material anatomical entity
- glial cell
- has plasma membrane part some integrin alpha-M
- has plasma membrane part some macrosialin
- has plasma membrane part some adhesion G protein-coupled receptor E1
- develops from some oligodendrocyte precursor cell
- capable of some innate immune response
Related from: