Terminology Service < Semantic Lookup Platform

professional antigen presenting cell

http://purl.obolibrary.org/obo/CL_0000145

Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.

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Term info

Label

professional antigen presenting cell

definition

A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.

has broad synonym

APC

has obo namespace

cell

imported from

http://purl.obolibrary.org/obo/cl.owl

Term relations

Equivalent to:

leukocyte and capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

Subclass of:

leukocyte
capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II