Terminology Service for NFDI4Health
dendritic cell
Go to external page
http://purl.obolibrary.org/obo/CL_0000451
Term info
Label
dendritic cell
definition
A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).
has obo namespace
cell
has related synonym
interdigitating cell, veiled cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- leukocyte and has part some MHC class II protein complex and bearer of some mononucleate and capable of some cytokine production and capable of some antigen processing and presentation of peptide or polysaccharide antigen via MHC class II and capable of some antigen processing and presentation and capable of some regulation of T cell differentiation and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD34 molecule and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
Subclass of:
- leukocyte
- mononuclear cell
- professional antigen presenting cell
- has part some MHC class II protein complex
- lacks_plasma_membrane_part some CD34 molecule
- lacks_plasma_membrane_part some neural cell adhesion molecule 1
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- lacks_plasma_membrane_part some CD19 molecule
- lacks_plasma_membrane_part some CD3 epsilon
- capable of some cytokine production
- capable of some regulation of T cell differentiation