Terminology Service for NFDI4Health
megakaryocyte progenitor cell
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http://purl.obolibrary.org/obo/CL_0000553
Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.
Term info
Label
megakaryocyte progenitor cell
definition
The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative).
has exact synonym
MkP, megakaryoblast, Meg-CFC, megacaryocyte progenitor cell, colony-forming unit-megakaryocyte, megakaryocytic progenitor cell, CFU-Meg, megacaryoblast
has obo namespace
cell
has related synonym
promegakaryocyte, promegacaryocyte
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- myeloid lineage restricted progenitor cell and capable of some endomitotic cell cycle and capable of some megakaryocyte differentiation and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
Subclass of:
- myeloid cell
- myeloid lineage restricted progenitor cell
- capable of some endomitotic cell cycle
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain
- lacks_plasma_membrane_part some CD4 molecule
- lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- lacks_plasma_membrane_part some CD3 epsilon
- lacks_plasma_membrane_part some CD2 molecule
- lacks_plasma_membrane_part some integrin alpha-M
- capable of some megakaryocyte differentiation
- lacks_plasma_membrane_part some CD14 molecule
- lacks_plasma_membrane_part some neural cell adhesion molecule 1
- lacks_plasma_membrane_part some CD19 molecule
- develops from some megakaryocyte-erythroid progenitor cell
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD5
- lacks_plasma_membrane_part some lymphocyte antigen 6G
Related from: