Terminology Service for NFDI4Health
basophil progenitor cell
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http://purl.obolibrary.org/obo/CL_0000613
BaP are also CD13-low and integrin beta-7-low. They are lin-negative (CD2, CD3e, CD4, CD5, CD8, CD11b, CD14, CD19, CD20, ly6g, ly76, and NCAM-1). They also lack expression of mast cell protease 1 (MCP-1) and microphthalmia-associated transcription factor (mitf).
Term info
Label
basophil progenitor cell
definition
A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa.
has obo namespace
cell
has related synonym
CFU-Bas, colony forming unit basophil, basophilic stem cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- granulocytopoietic cell and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and has part some endothelial transcription factor GATA-2 and capable of some basophil differentiation and has_high_plasma_membrane_amount some high affinity immunoglobulin epsilon receptor subunit alpha and has_low_plasma_membrane_amount some transmembrane emp24 domain-containing protein 1 and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some mast/stem cell growth factor receptor and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
Subclass of:
- granulocytopoietic cell
- material anatomical entity
- myeloid cell
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain
- lacks_plasma_membrane_part some CD4 molecule
- lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1
- lacks_plasma_membrane_part some CD3 epsilon
- has_high_plasma_membrane_amount some high affinity immunoglobulin epsilon receptor subunit alpha
- has part some CCAAT/enhancer-binding protein alpha
- lacks_plasma_membrane_part some CD2 molecule
- lacks_plasma_membrane_part some integrin alpha-M
- has part some erythroid transcription factor
- develops from some basophil mast progenitor cell
- capable of some basophil differentiation
- lacks_plasma_membrane_part some CD14 molecule
- lacks_plasma_membrane_part some neural cell adhesion molecule 1
- lacks_plasma_membrane_part some mast/stem cell growth factor receptor
- lacks_plasma_membrane_part some CD19 molecule
- has_low_plasma_membrane_amount some transmembrane emp24 domain-containing protein 1
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD5
- has part some endothelial transcription factor GATA-2
- lacks_plasma_membrane_part some lymphocyte antigen 6G
Related from: