myeloid dendritic cell
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http://purl.obolibrary.org/obo/CL_0000782
These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).
Term info
Label
myeloid dendritic cell
definition
A dendritic cell of the myeloid lineage.
has exact synonym
CD11c+CD123- DC, mDC
has broad synonym
interdigitating cell, veiled cell
has obo namespace
cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- conventional dendritic cell and develops from some myeloid cell and lacks_plasma_membrane_part some interleukin-3 receptor class 2 alpha chain