Terminology Service for NFDI4Health
immature single positive thymocyte
Go to external page
http://purl.obolibrary.org/obo/CL_0000805
Note that this type of thymocyte has passed the beta-selection checkpoint and is rapidly proliferating and rearranging the T cell receptor alpha chain and expressing the CD8 coreceptor. This stage comes between the DN4 and DP stages.
Term info
Label
immature single positive thymocyte
definition
A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive.
has exact synonym
immature single positive T lymphocyte, ISP, immature single positive T-lymphocyte, immature single positive T cell, T.ISP.th
has obo namespace
cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- thymocyte and has plasma membrane part some pre-T cell receptor complex and has plasma membrane part some T cell receptor co-receptor CD8 and has_high_plasma_membrane_amount some signal transducer CD24 and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some CD44 molecule and lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha
Subclass of:
- material anatomical entity
- thymocyte
- has plasma membrane part some T cell receptor co-receptor CD8
- lacks_plasma_membrane_part some CD4 molecule
- develops from some DN4 thymocyte
- lacks_plasma_membrane_part some interleukin-2 receptor subunit alpha
- has_high_plasma_membrane_amount some signal transducer CD24
- lacks_plasma_membrane_part some CD44 molecule
- has plasma membrane part some pre-T cell receptor complex
Related from: