Terminology Service for NFDI4Health
DN2 thymocyte
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http://purl.obolibrary.org/obo/CL_0000806
Note that this type of thymocyte is at the earliest stage of T cell receptor rearrangement of the beta, gamma, and delta T cell receptor chains. Also, there is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.
Term info
Label
DN2 thymocyte
definition
A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive.
has exact synonym
DN2 alpha-beta immature T-cell, DN2 cell, TN2 cell, double negative 2, TN2 thymocyte, preT.DN2.Th, DN2 alpha-beta immature T-lymphocyte, DN2 immature T cell, DN2 alpha-beta immature T lymphocyte
has obo namespace
cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- thymocyte and has plasma membrane part some CD44 molecule and has plasma membrane part some interleukin-2 receptor subunit alpha and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some T cell receptor co-receptor CD8
Subclass of:
- thymocyte
- material anatomical entity
- double negative thymocyte
- develops from some DN1 thymic pro-T cell
- has plasma membrane part some CD44 molecule
- has plasma membrane part some interleukin-2 receptor subunit alpha
Related from: