Terminology Service for NFDI4Health
DN3 thymocyte
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http://purl.obolibrary.org/obo/CL_0000807
There is growing evidence that molecular markers characterizing double negative thymocytes are different across species, especially in mouse versus human thymus. If in doubt, please consider using CL:0002489 'double negative thymocyte'.
Term info
Label
DN3 thymocyte
definition
A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain.
has exact synonym
TN3 thymocyte, preT.DN3.Th, double negative 3, DN3 cell, TN3 cell, DN3 alpha-beta immature T-lymphocyte, DN3 immature T cell, DN3 alpha-beta immature T-cell, DN3 alpha-beta immature T lymphocyte
has broad synonym
early cortical thymocyte
has obo namespace
cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- thymocyte and has plasma membrane part some pre-T cell receptor complex and has plasma membrane part some interleukin-2 receptor subunit alpha and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some CD44 molecule and lacks_plasma_membrane_part some T cell receptor co-receptor CD8
Subclass of:
- thymocyte
- material anatomical entity
- double negative thymocyte
- develops from some DN2 thymocyte
- has plasma membrane part some interleukin-2 receptor subunit alpha
- lacks_plasma_membrane_part some CD44 molecule
- has plasma membrane part some pre-T cell receptor complex
Related from: