Terminology Service for NFDI4Health
pro-NK cell
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http://purl.obolibrary.org/obo/CL_0000825
Most markers only described for human pro NK cells.
Term info
Label
pro-NK cell
definition
A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative.
has exact synonym
pro-natural killer cell, NKP, natural killer cell progenitor
has obo namespace
cell
has related synonym
null cell, preNK cell
imported from
http://purl.obolibrary.org/obo/cl.owl
Term relations
Equivalent to:
- lymphoid lineage restricted progenitor cell and has plasma membrane part some CD34 molecule and has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45RA and has plasma membrane part some interleukin-2 receptor subunit beta and has plasma membrane part some neprilysin and lacks_plasma_membrane_part some KLRB1-like protein and lacks_plasma_membrane_part some mast/stem cell growth factor receptor
Subclass of:
- lymphoid lineage restricted progenitor cell
- material anatomical entity
- has plasma membrane part some interleukin-2 receptor subunit beta
- lacks_plasma_membrane_part some KLRB1-like protein
- lacks_plasma_membrane_part some mast/stem cell growth factor receptor
- develops from some common lymphoid progenitor
- has plasma membrane part some CD34 molecule
- has plasma membrane part some receptor-type tyrosine-protein phosphatase C isoform CD45RA
- has plasma membrane part some neprilysin
Related from: