Terminology Service for NFDI4Health

nucleolus

Go to external page http://purl.obolibrary.org/obo/GO_0005730


Term info

Label

nucleolus

database cross reference
Subsets

goslim_chembl, goslim_generic, goslim_drosophila, goslim_pir, goslim_plant, goslim_yeast, goslim_candida, goslim_aspergillus

definition

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

has obo namespace

cellular_component

id

GO:0005730

imported from

http://purl.obolibrary.org/obo/cl.owl