A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

cell surface receptor linked signalling pathway, cell surface receptor linked signal transduction, cell surface receptor linked signaling pathway

biological_process

GO:0007166

http://purl.obolibrary.org/obo/cl.owl