Terminology Service for NFDI4Health
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apoptotic signaling pathway

Go to external page http://purl.obolibrary.org/obo/GO_0097190

This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.

Term info

Label

apoptotic signaling pathway

creation date

2011-11-23T09:30:23Z

definition

A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.

has exact synonym

apoptotic signalling pathway, induction of apoptosis by extracellular signals

has alternative id

GO:0008624

has obo namespace

biological_process

id

GO:0097190

imported from

http://purl.obolibrary.org/obo/cl.owl

Term relations