Terminology Service for NFDI4Health
secondary cultured cell population
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http://purl.obolibrary.org/obo/OBI_0001905
The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally.
Term info
Label
secondary cultured cell population
Synonyms
- secondary cell culture sample
definition
A cultured cell population that is derived through one or more passages in culture.
definition source
PERSON:Matthew Brush
editor note
The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage. We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line. Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture.
editor preferred label
secondary cultured cell population
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
imported from
http://purl.obolibrary.org/obo/obi.owl
term editor
PERSON:Matthew Brush
Term relations
Subclass of:
- cultured cell population
- has grain only secondary cultured cell
- has grain some secondary cultured cell
- is_specified_output_of some cell culture splitting