Terminology Service for NFDI4Health
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heart

Go to external page http://purl.obolibrary.org/obo/UBERON_0000948

Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706

Term info

Label

heart

database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core, organ_slim, major_organ

axiom lost from external ontology

relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]

definition

A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.

external definition

Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO], Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]

has exact synonym

vertebrate heart, chambered heart

has narrow synonym

branchial heart

homology notes

As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]

id

UBERON:0000948

imported from

http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl

never in taxon

http://purl.obolibrary.org/obo/NCBITaxon_6239, http://purl.obolibrary.org/obo/NCBITaxon_7227