Terminology Service for NFDI4Health

dorsal pancreatic bud

Go to external page http://purl.obolibrary.org/obo/UBERON_0003923


Term info

Label

dorsal pancreatic bud

database cross reference
Subsets

efo_slim, vertebrate_core

definition

Pancreatic bud that gives rise to the accessory pancreatic duct.

depicted by

http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png

external definition

The pancreatic bud that gives rise to the accessory pancreatic duct.[AAO]

has exact synonym

pancreas primordium dorsal bud, primary pancreatic bud, pancreas dorsal primordium duct bud

has related synonym

dorsal pancreatic anlage, posterior pancreatic anlage, dorsal pancreas anlage, posterior pancreatic bud

homology notes

In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]

id

UBERON:0003923

imported from

http://purl.obolibrary.org/obo/uberon.owl, http://purl.obolibrary.org/obo/cl.owl