Terminology Service for NFDI4Health

execution phase of apoptosis

Go to external page http://purl.obolibrary.org/obo/GO_0097194


A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [ http://www.ncbi.nlm.nih.gov/pubmed/21760595 ]

Term info

Label

execution phase of apoptosis

Synonyms
  • execution phase of apoptotic process
IAO 0000412

http://purl.obolibrary.org/obo/go.owl

created by

paola

creation date

2011-11-23T09:45:24Z

has narrow synonym

apoptosis

has obo namespace

biological_process

id

GO:0097194