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aldosterone

Go to external page http://purl.obolibrary.org/obo/CHEBI_27584

A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.

A 18-oxo steroid that has formula C21H28O5.

Term info

Label

aldosterone

Synonyms
  • (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al
  • 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al
  • C21H28O5
  • InChI=1/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
  • InChIKey=PQSUYGKTWSAVDQ-ZVIOFETBBV
  • [H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO
database cross reference
EFO URI

http://www.ebi.ac.uk/efo/EFO_0001479

definition citation

CHEBI_27584

Term relations