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oxazepam

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Human PLAC8 wild-type allele is located in the vicinity of 4q21.22 and is approximately 24 kb in length. This allele, which encodes placenta-specific gene 8 protein, may play a role in the modulation of dendritic cell activity. Aberrant expression of the gene may be involved in leukemia relapse.

A 1,4-benzodiazepinone that has formula C15H11ClN2O2.

A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation. (NCI04)

Term info

Label

oxazepam

Synonyms
  • (H115D)VHL35
  • (H115D)VHL35 Peptide
  • (RS)-Oxazepam
  • 7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  • C15H11ClN2O2
  • InChI=1/C15H11ClN2O2/c16-10-6-7-12-11(8-10)13(9-4-2-1-3-5-9)18-15(20)14(19)17-12/h1-8,15,20H,(H,17,19)/f/h17H
  • InChIKey=ADIMAYPTOBDMTL-HCKMINDGCL
  • OC1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=O
  • Onzin
  • PLAC8 wt Allele
  • Placenta-Specific 8 wt Allele
  • Serax
  • Tazepam
database cross reference
definition citation

7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 21087, 1087, C15H11ClN2O2, 604-75-1

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