Terminology Service for NFDI4Health
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endothelial cell

Go to external page http://purl.obolibrary.org/obo/CL_0000115

An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. [ http://www.ncbi.nlm.nih.gov/pubmed/21275341 http://en.wikipedia.org/wiki/Endothelial_cell http://id.nlm.nih.gov/mesh/D042783 https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855 ]

Term info

Label

endothelial cell

Synonyms
  • endotheliocyte
database cross reference
Subsets

human_reference_atlas

RO 0002175

http://purl.obolibrary.org/obo/NCBITaxon_9606

comment

From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard].