A brain disease that is characterized by functional impairment of cognition, cerebral signal conduction, neurotransmission and synaptic plasticity, and underlying structural pathology associated with diabetes. [ http://www.ncbi.nlm.nih.gov/pubmed/20798963 http://link.springer.com/chapter/10.1007%2F978-1-59745-311-0_11#page-1 ]