Terminology Service for NFDI4Health
nephron
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http://purl.obolibrary.org/obo/UBERON_0001285
The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]. [ http://www.ncbi.nlm.nih.gov/pubmed/9268568 http://en.wikipedia.org/wiki/Nephron ]
Term info
Label
nephron
Subsets
uberon_slim, pheno_slim, vertebrate_core, human_reference_atlas
RO 0002175
http://purl.obolibrary.org/obo/NCBITaxon_9606
depicted by
http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png
editor note
kidney terms require review for cross-vertebrate compatibility and developmental relationships.
external definition
Functional unit of the kidney that filters waste.[TAO]
has narrow synonym
mature nephron
has obo namespace
uberon
has related synonym
nephroneum, tubulus renalis
id
UBERON:0001285
taxon notes
In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)