Terminology Service for NFDI4Health

forebrain

Go to external page http://purl.obolibrary.org/obo/UBERON_0001890


The most anterior region of the brain including both the telencephalon and diencephalon. [ http://zfin.org/ZDB-PUB-961014-576 http://en.wikipedia.org/wiki/Forebrain ]

Term info

Label

forebrain

database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core, human_reference_atlas

RO 0002175

http://purl.obolibrary.org/obo/NCBITaxon_9606

axiom lost from external ontology

relationship loss: develops_from forebrain neural tube (TAO:0007041)[TAO]

depicted by

http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg

external definition

The most anterior region the brain including both the telencephalon and diencephalon. Kimmel et al, 1995.[TAO], Most anterior of the three regions of the brain consisting of the telencephalon and diencephalon.[AAO]

has related synonym

prosencephalon

has relational adjective

prosencephalic

homology notes

In craniate embryos, neural expression of Distal-less-related genes is exclusively in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll is in the anterior three-fourths of the cerebral vesicle, we suggest that this region of the neural tube is homologous to parts of the craniate forebrain. This conclusion is strongly supported by three-dimensional, computer-assisted reconstruction of the neural tube of amphioxus based on serial transmission electron microscopy. At the neuroanatomical level, a number of detailed homologies are indicated between the anterior three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the craniate forebrain. If one assumes that the amphioxus condition fairly represents the nervous system of the proximate ancestor of the craniates, one can suggest that they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG]

id

UBERON:0001890