Terminology Service for NFDI4Health
midbrain
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http://purl.obolibrary.org/obo/UBERON_0001891
The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. [ http://amigo.geneontology.org/amigo/term/GO:0030901 ]
Term info
Label
midbrain
Subsets
uberon_slim, efo_slim, pheno_slim, vertebrate_core, human_reference_atlas
RO 0002171
http://purl.obolibrary.org/obo/UBERON_0001894, http://purl.obolibrary.org/obo/UBERON_0002028
RO 0002175
http://purl.obolibrary.org/obo/NCBITaxon_9606
depicted by
http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG
editor note
developmental relationships need revised
external definition
The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally. Kimmel et al, 1995.[TAO], Middle part of the brain composed of the optic tectum and penducular region.[AAO]
external ontology notes
part of brainstem in ABA - we reject this in favor of ISBN:0471888893 which has an implicit overlaps relationships
has obo namespace
uberon
has related synonym
mesencephalon
has relational adjective
mesencephalic
homology notes
Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]
id
UBERON:0001891