Terminology Service for NFDI4Health

hypothalamus

Go to external page http://purl.obolibrary.org/obo/UBERON_0001898


A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. [ http://en.wikipedia.org/wiki/Hypothalamus http://zfin.org/curator ]

Term info

Label

hypothalamus

Synonyms
  • preoptico-hypothalamic area
  • preoptico-hypothalamic region
database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core, human_reference_atlas

RO 0002171

http://purl.obolibrary.org/obo/UBERON_0001897

RO 0002175

http://purl.obolibrary.org/obo/NCBITaxon_7742, http://purl.obolibrary.org/obo/NCBITaxon_9606, http://purl.obolibrary.org/obo/NCBITaxon_117569

depicted by

http://upload.wikimedia.org/wikipedia/commons/9/9f/LocationOfHypothalamus.jpg

dubious for taxon

http://purl.obolibrary.org/obo/NCBITaxon_7737

external definition

Part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system.[AAO], A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. Kimmel et al, 1995.[TAO]

has related synonym

hypothalamus

homology notes

For instance, the vertebrate ventral diencephalon generates the hypothalamus which functions as a major endocrine center in cooperation with the hypophysis, the anterior part of the pituitary gland, located just ventral to the hypothalamus. In the amphioxus brain, the presence of a hypothalamus-like structure has been reported associated with the ventrally located Hatschek's pit, the hypothetical hypophysial homologue. It is thus conceivable that a hypothalamus-like structure originally involved in endocrine functions may have already been present before the establishment of vertebrates.[well established][VHOG]

id

UBERON:0001898

taxon notes

all vertebrates contain a hypothalamus