Terminology Service for NFDI4Health
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neoplasm of mature B-cells

Go to external page http://www.ebi.ac.uk/efo/EFO_0000096

A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). [ ]

Term info

Label

neoplasm of mature B-cells

Synonyms
  • mature B-cell lymphocytic neoplasm
  • mature B-cell neoplasm
  • neoplasm of mature B-cells
database cross reference
closeMatch

http://identifiers.org/snomedct/40411000, http://identifiers.org/snomedct/55150002, http://identifiers.org/snomedct/46744002, http://linkedlifedata.com/resource/umls/id/CL448793, http://identifiers.org/snomedct/55020008

comment

Editor note: is a non-hodgkin in ONCOTREE

exactMatch

http://linkedlifedata.com/resource/umls/id/C1334633, http://purl.obolibrary.org/obo/NCIT_C27910, http://purl.obolibrary.org/obo/DOID_706, http://identifiers.org/snomedct/269476000

gwas trait

true

has related synonym

mature B-cell neoplasms

id

EFO:0000096