Terminology Service for NFDI4Health
myelodysplastic syndrome
Go to external page
http://www.ebi.ac.uk/efo/EFO_0000198
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) [ ]
Term info
Label
myelodysplastic syndrome
Synonyms
- MDS
- dysmyelopoietic syndrome
- hematopoeitic - myelodysplastic syndrome (MDS)
- myelodysplasia
- myelodysplastic neoplasm
- myelodysplastic syndrome
- myelodysplastic syndrome, somatic
- myelodysplastic syndrome/neoplasm
- myelodysplastic syndromes
- oligoblastic leukemia
- preleukemia
- smoldering leukemia
Subsets
disease_grouping, ordo_group_of_disorders
closeMatch
http://identifiers.org/meddra/10028532
exactMatch
http://purl.obolibrary.org/obo/Orphanet_52688, https://omim.org/entry/614286, http://linkedlifedata.com/resource/umls/id/C3463824, http://purl.obolibrary.org/obo/NCIT_C3247, http://linkedlifedata.com/resource/umls/id/C0033027, http://purl.obolibrary.org/obo/DOID_0050908, http://identifiers.org/snomedct/109995007
gwas trait
true
has related synonym
myelodysplastic syndrome, susceptibility to
id
EFO:0000198
see also
https://github.com/monarch-initiative/mondo/issues/4521