Terminology Service for NFDI4Health
CCL2 measurement
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http://www.ebi.ac.uk/efo/EFO_0004749
Is the quantification of Chemokine (C-C motif) ligand 2, involved in response to infection and inflammation. Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. CCL2 is reported to be associated with Alzheimer's disease e.g. http://www.ncbi.nlm.nih.gov/pubmed/22303443 and http://europepmc.org/abstract/MED/25340798
Term info
Label
CCL2 measurement
Synonyms
- MCP-1 measurement
- MCP1 measurement
- chemokine CCL2 level
- chemokine CCL2 levels
- monocyte chemoattractant protein-1 measurement
- monocyte chemotactic protein-1 level
- monocyte chemotactic protein-1 levels
- monocyte chemotactic protein-1 measurement
definition citation
http://en.wikipedia.org/wiki/CCL2, http://www.uniprot.org/uniprot/P13500
gwas trait
true
term editor
Helen Parkinson
Term relations
Subclass of:
- cytokine measurement
- Alzheimer's disease biomarker measurement
- is_about some Alzheimer disease
- is_about some cytokine