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atrial natriuretic factor measurement

Go to external page http://www.ebi.ac.uk/efo/EFO_0004789

Is a quantification of the 126-amino acid C-terminal fragment of the ANP precursor, an approximately 150-amino acid polypeptide in a number of species. It is formed by the removal of the N-terminal signal sequence ANP (1-24). This prohormone contains various active ANF sequences. ANF is is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells.[1][2][3] It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). Increased levels of ANP are associated with heart failure.

Term info

Label

atrial natriuretic factor measurement

comment

is about MeSH:D017461

definition citation

http://en.wikipedia.org/wiki/Atrial_natriuretic_factor

gwas trait

true

term editor

Helen Parkinson