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tissue plasminogen activator measurement

Go to external page http://www.ebi.ac.uk/efo/EFO_0004791

Is a quantification of tissue plasminogen activator, an enzyme which converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Play a direct role in facilitating neuronal migration.

Term info

Label

tissue plasminogen activator measurement

definition citation

http://europepmc.org/abstract/MED/24578379, http://www.uniprot.org/uniprot/P00750

gwas trait

true

term editor

Helen Parkinson