Terminology Service for NFDI4Health
endothelial dysfunction
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http://www.ebi.ac.uk/efo/EFO_1001461
In vascular diseases, endothelial dysfunction is a systemic pathological state of the endothelium (the inner lining of blood vessels) and can be broadly defined as an imbalance between vasodilating and vasoconstricting substances produced by (or acting on) the endothelium. Normal functions of endothelial cells include mediation of coagulation, platelet adhesion, immune function and control of volume and electrolyte content of the intravascular and extravascular spaces.
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Subclass of:
- vascular disease
- has_disease_location some (endothelium or part of some endothelium)
- has_disease_location some endothelial cell