Terminology Service for NFDI4Health

cytoplasmic exosome (RNase complex)

Go to external page http://purl.obolibrary.org/obo/GO_0000177


A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. [ http://www.ncbi.nlm.nih.gov/pubmed/17174896 http://www.ncbi.nlm.nih.gov/pubmed/20531386 http://www.ncbi.nlm.nih.gov/pubmed/26726035 ]

Term info

Label

cytoplasmic exosome (RNase complex)

Synonyms
  • cytoplasmic exosome (ribonuclease complex)
  • cytoplasmic exosome multienzyme ribonuclease complex
  • prokaryotic exosome multienzyme ribonuclease complex
has obo namespace

cellular_component

id

GO:0000177

Term relations