Terminology Service for NFDI4Health

exosome (RNase complex)

Go to external page http://purl.obolibrary.org/obo/GO_0000178


A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. [ http://www.ncbi.nlm.nih.gov/pubmed/26726035 http://www.ncbi.nlm.nih.gov/pubmed/17174896 http://www.ncbi.nlm.nih.gov/pubmed/20531386 ]

Term info

Label

exosome (RNase complex)

Synonyms
  • exosome (ribonucleasease complex)
  • exosome multienzyme ribonuclease complex
Subsets

goslim_pir

comment

Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies.

has obo namespace

cellular_component

id

GO:0000178

Term relations